Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0K0KP
|
|||
| Former ID |
DIB008391
|
|||
| Drug Name |
GE-68
|
|||
| Synonyms |
GE-68; GE 68; 158358-22-6; CHEMBL93812; AC1L322R; SCHEMBL9738669; (+-)-3-(2-Phenylethyl)-alpha-((propylamino)methyl)-2-benzofuranmethanol; 1-(3-phenethyl-1-benzofuran-2-yl)-2-(propylamino)ethanol; 2-(Propylamino)-1-[3-(2-phenylethyl)benzofuran-2-yl]ethanol; 2-Benzofuranmethanol, 3-(2-phenylethyl)-alpha-((propylamino)methyl)-, (+-)-
Click to Show/Hide
|
|||
| Drug Type |
Small molecular drug
|
|||
| Indication | Heart arrhythmia [ICD-11: BC65; ICD-10: I49, I49.8] | Terminated | [1] | |
| Company |
University of Vienna
|
|||
| Structure |
 |
Download2D MOL |
||
| Formula |
C21H25NO2
|
|||
| Canonical SMILES |
CCCNCC(C1=C(C2=CC=CC=C2O1)CCC3=CC=CC=C3)O
|
|||
| InChI |
1S/C21H25NO2/c1-2-14-22-15-19(23)21-18(13-12-16-8-4-3-5-9-16)17-10-6-7-11-20(17)24-21/h3-11,19,22-23H,2,12-15H2,1H3
|
|||
| InChIKey |
XPEXCFSBFPOSQR-UHFFFAOYSA-N
|
|||
| CAS Number |
CAS 158358-22-6
|
|||
| PubChem Compound ID | ||||
| PubChem Substance ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Sodium channel unspecific (NaC) | Target Info | Modulator | [2] |
| KEGG Pathway | Dopaminergic synapse | |||
| Reactome | Interaction between L1 and Ankyrins | |||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800001596) | |||
| REF 2 | Electrophysiological properties of the propafenone-analogue GE 68 (1-[3-(phenylethyl)-2-benzofuryl]-2-(propylamino)-ethanol) in isolated preparations and ventricular myocytes of guinea-pig hearts. Naunyn Schmiedebergs Arch Pharmacol. 1997 Feb;355(2):230-8. | |||
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.