Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0K0GN
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| Former ID |
DIB004754
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| Drug Name |
LDI-200
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| Synonyms |
Chorionic gonadotropin, Milkhaus; HCG, Milkhaus; Oncology therapeutics, Milkhaus
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| Indication | leukaemia [ICD-11: 2A60-2B33; ICD-9: 208.9] | Discontinued in Phase 3 | [1] | |
| Company |
Milkhaus Laboratory Inc
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Luteinizing hormone receptor (LHCGR) | Target Info | Modulator | [2] |
| KEGG Pathway | Calcium signaling pathway | |||
| Neuroactive ligand-receptor interaction | ||||
| Ovarian steroidogenesis | ||||
| Prolactin signaling pathway | ||||
| NetPath Pathway | FSH Signaling Pathway | |||
| Pathwhiz Pathway | Intracellular Signalling Through LHCGR Receptor and Luteinizing Hormone/Choriogonadotropin | |||
| Pathway Interaction Database | Arf6 signaling events | |||
| Reactome | Hormone ligand-binding receptors | |||
| G alpha (s) signalling events | ||||
| WikiPathways | GPCRs, Class A Rhodopsin-like | |||
| Ovarian Infertility Genes | ||||
| Peptide GPCRs | ||||
| GPCR ligand binding | ||||
| GPCR downstream signaling | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800006739) | |||
| REF 2 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 254). | |||
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