Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0JU5X
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| Drug Name |
Bardoxolone methyl
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| Synonyms |
BARD; WPTTVJLTNAWYAO-OYWPANLISA-N; 218600-53-4
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| Drug Type |
Small molecular drug
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| Indication | Mixed connective tissue disease [ICD-11: 4A43.3; ICD-10: M35, M35.1] | Phase 3 | [1] | |
| Pulmonary arterial hypertension [ICD-11: BB01.0; ICD-9: 416] | Phase 2 | [2] | ||
| Pulmonary hypertension [ICD-11: BB01; ICD-10: I27, I27.0; ICD-9: 416] | Phase 2 | [1] | ||
| Company |
Reata Pharmaceuticals Irving, TX
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| Structure |
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Download2D MOL |
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| Formula |
C32H43NO4
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| Canonical SMILES |
CC1(CCC2(CCC3(C(C2C1)C(=O)C=C4C3(CCC5C4(C=C(C(=O)C5(C)C)C#N)C)C)C)C(=O)OC)C
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| InChI |
1S/C32H43NO4/c1-27(2)11-13-32(26(36)37-8)14-12-31(7)24(20(32)17-27)21(34)15-23-29(5)16-19(18-33)25(35)28(3,4)22(29)9-10-30(23,31)6/h15-16,20,22,24H,9-14,17H2,1-8H3/t20-,22-,24-,29-,30+,31+,32-/m0/s1
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| InChIKey |
WPTTVJLTNAWYAO-KPOXMGGZSA-N
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| CAS Number |
CAS 218600-53-4
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| PubChem Compound ID | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA) | |||
| REF 2 | Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA) | |||
| REF 3 | A synthetic triterpenoid, 2-cyano-3,12-dioxooleana-1,9-dien-28-oic acid (CDDO), is a ligand for the peroxisome proliferator-activated receptor gamma. Mol Endocrinol. 2000 Oct;14(10):1550-6. | |||
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