Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D0JL3O
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| Former ID |
DNC010649
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| Drug Name |
NICARBAZIN
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| Synonyms |
Nicarbazin; 330-95-0; Nicarbazine; Nicrazine; Nicrazin; Nicoxin; Nirazin; Nicarb; Nicarbasin; Nicarbazin [BAN]; MK 75; UNII-11P9NUA12U; MK 75 (VAN); HSDB 7466; NSC 7171; EINECS 206-359-1; AI3-60130; 11P9NUA12U; CHEBI:81725; Urea, N,N'-bis(4-nitrophenyl)-, compd. with 4,6-dimethyl-2(1H)-pyrimidinone (1:1); 4,4'-Dinitrocarbanilide, 4,6-dimethyl-2-pyrimidinol; 1,3-bis(4-nitrophenyl)urea; 4,6-dimethyl-1H-pyrimidin-2-one; N,N'-Bis(4-nitrophenyl)urea compd. with 4,6-dimethyl-2-pyrimidinol (1:1); W-106788
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
 |
Download2D MOL |
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| Formula |
C19H18N6O6
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| Canonical SMILES |
CC1=CC(=NC(=O)N1)C.C1=CC(=CC=C1NC(=O)NC2=CC=C(C=C2)[N+](=O)[O-])[N+](=O)[O-]
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| InChI |
1S/C13H10N4O5.C6H8N2O/c18-13(14-9-1-5-11(6-2-9)16(19)20)15-10-3-7-12(8-4-10)17(21)22;1-4-3-5(2)8-6(9)7-4/h1-8H,(H2,14,15,18);3H,1-2H3,(H,7,8,9)
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| InChIKey |
UKHWDRMMMYWSFL-UHFFFAOYSA-N
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| CAS Number |
CAS 330-95-0
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| PubChem Compound ID | ||||
| ChEBI ID |
CHEBI:81725
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Fatty acid amide hydrolase (FAAH) | Target Info | Inhibitor | [1] |
| BioCyc | Anandamide degradation | |||
| KEGG Pathway | Retrograde endocannabinoid signaling | |||
| Panther Pathway | Anandamide degradation | |||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Mining biologically-active molecules for inhibitors of fatty acid amide hydrolase (FAAH): identification of phenmedipham and amperozide as FAAH inh... Bioorg Med Chem Lett. 2009 Dec 1;19(23):6793-6. | |||
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