Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0JJ1B
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| Former ID |
DIB012212
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| Drug Name |
Artilide
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| Synonyms |
Artilide fumarate; U-88943E
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| Drug Type |
Small molecular drug
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| Indication | Cardiac arrhythmias [ICD-11: BC9Z; ICD-9: 427] | Discontinued in Phase 1 | [1] | |
| Company |
Pharmacia & Upjohn Co
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| Structure |
 |
Download2D MOL |
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| Formula |
C19H34N2O3S
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| Canonical SMILES |
CCCCN(CCCC)CCCC(C1=CC=C(C=C1)NS(=O)(=O)C)O
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| InChI |
1S/C19H34N2O3S/c1-4-6-14-21(15-7-5-2)16-8-9-19(22)17-10-12-18(13-11-17)20-25(3,23)24/h10-13,19-20,22H,4-9,14-16H2,1-3H3/t19-/m1/s1
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| InChIKey |
UAARDOOBGJGDJV-LJQANCHMSA-N
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| CAS Number |
CAS 133267-19-3
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Sodium channel unspecific (NaC) | Target Info | Modulator | [2], [3] |
| KEGG Pathway | Dopaminergic synapse | |||
| Reactome | Interaction between L1 and Ankyrins | |||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800002256) | |||
| REF 2 | Potassium channel blockers as antiarrhythmic drugs. Drug Development Research Volume 33, Issue 3, pages 235-249, November 1994. | |||
| REF 3 | Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015 | |||
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