Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0JI1J
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| Former ID |
DIB009306
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| Drug Name |
GP-683
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| Synonyms |
Analgesic-sparing agent, Univ Texas
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| Drug Type |
Small molecular drug
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| Indication | Pain [ICD-11: MG30-MG3Z] | Terminated | [1] | |
| Company |
Metabasis Therapeutics Inc
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| Structure |
 |
Download2D MOL |
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| Formula |
C23H22N4O3
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| Canonical SMILES |
CC1C(C(C(O1)N2C=C(C3=C(N=CN=C32)NC4=CC=CC=C4)C5=CC=CC=C5)O)O
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| InChI |
1S/C23H22N4O3/c1-14-19(28)20(29)23(30-14)27-12-17(15-8-4-2-5-9-15)18-21(24-13-25-22(18)27)26-16-10-6-3-7-11-16/h2-14,19-20,23,28-29H,1H3,(H,24,25,26)/t14-,19-,20-,23-/m1/s1
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| InChIKey |
YPWISWJHVQIXIL-DVHMWJAFSA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Adenosine kinase (ADK) | Target Info | Inhibitor | [2] |
| BioCyc | Superpathway of purine nucleotide salvage | |||
| Adenine and adenosine salvage II | ||||
| KEGG Pathway | Purine metabolism | |||
| Metabolic pathways | ||||
| Reactome | Purine salvage | |||
| WikiPathways | Metabolism of nucleotides | |||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800006618) | |||
| REF 2 | The effect of GP683, an adenosine kinase inhibitor, on the desflurane anesthetic requirement in dogs. Anesth Analg. 1997 Sep;85(3):675-80. | |||
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