Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D0J9SS
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| Former ID |
DNC011764
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| Drug Name |
6-Nitro-2-(3-nitro-phenyl)-chromen-4-one
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| Synonyms |
6,3'-Dinitroflavone; 3',6-Dinitroflavone; 100914-36-1; 4H-1-Benzopyran-4-one,6-nitro-2-(3-nitrophenyl)-; 6-3'-Dinitroflavone; ACMC-20m3ym; AC1L2SI8; 6-Nitro-2-(3-nitrophenyl)-4H-1-benzopyran-4-one; SCHEMBL4607216; CHEMBL292868; CTK3J9355; DTXSID90143576; AKOS030553659
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C15H8N2O6
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| Canonical SMILES |
C1=CC(=CC(=C1)[N+](=O)[O-])C2=CC(=O)C3=C(O2)C=CC(=C3)[N+](=O)[O-]
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| InChI |
1S/C15H8N2O6/c18-13-8-15(9-2-1-3-10(6-9)16(19)20)23-14-5-4-11(17(21)22)7-12(13)14/h1-8H
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| InChIKey |
CNVQMRWAJHEFGZ-UHFFFAOYSA-N
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| CAS Number |
CAS 100914-36-1
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | GABA(A) receptor alpha-1 (GABRA1) | Target Info | Inhibitor | [1] |
| GABA(A) receptor gamma-2 (GABRG2) | Target Info | Inhibitor | [1] | |
| Gamma-aminobutyric acid receptor (GAR) | Target Info | Inhibitor | [1] | |
| KEGG Pathway | Neuroactive ligand-receptor interaction | |||
| Retrograde endocannabinoid signaling | ||||
| GABAergic synapse | ||||
| Morphine addiction | ||||
| Nicotine addiction | ||||
| Reactome | Ligand-gated ion channel transport | |||
| GABA A receptor activation | ||||
| WikiPathways | SIDS Susceptibility Pathways | |||
| Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell | ||||
| Iron uptake and transport | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | 6,3'-Dinitroflavone, a novel high affinity ligand for the benzodiazepine receptor with potent anxiolytic properties, Bioorg. Med. Chem. Lett. 5(22):2717-2720 (1995). | |||
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