Drug Information
Drug General Information | Top | |||
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Drug ID |
D0J9JQ
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Former ID |
DIB007748
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Drug Name |
XR-5082
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Synonyms |
Plasminogen activator inhibitor inhibitor, Xenova
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Drug Type |
Small molecular drug
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Indication | Thrombosis [ICD-11: DB61-GB90; ICD-10: I80-I82] | Terminated | [1] | |
Company |
Xenova Ltd
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Structure |
Download2D MOL |
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Formula |
C22H23N3O2S
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Canonical SMILES |
CN(C)CCSC1=CC=C(C=C1)C=C2C(=O)NC(=CC3=CC=CC=C3)C(=O)N2
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InChI |
1S/C22H23N3O2S/c1-25(2)12-13-28-18-10-8-17(9-11-18)15-20-22(27)23-19(21(26)24-20)14-16-6-4-3-5-7-16/h3-11,14-15H,12-13H2,1-2H3,(H,23,27)(H,24,26)/b19-14+,20-15-
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InChIKey |
RYRKPESQGOEIQY-WOBBTWAASA-N
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CAS Number |
CAS 174849-68-4
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PubChem Compound ID |
Target and Pathway | Top | |||
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Target(s) | Plasminogen activator inhibitor (PAI) | Target Info | Inhibitor | [2] |
KEGG Pathway | HIF-1 signaling pathway | |||
p53 signaling pathway | ||||
Hippo signaling pathway | ||||
Complement and coagulation cascades | ||||
Chagas disease (American trypanosomiasis) |
References | Top | |||
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REF 1 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800006901) | |||
REF 2 | Evaluation of a low molecular weight modulator of human plasminogen activator inhibitor-1 activity. Thromb Haemost. 1996 May;75(5):808-15. |
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