Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0J8IJ
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| Former ID |
DNCL003543
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| Drug Name |
Eliglustat tartrate
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| Synonyms |
Fabrazyme (TN)
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| Drug Type |
Small molecular drug
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| Indication | Metabolic disorder [ICD-11: 5C50-5D2Z; ICD-10: E70-E90; ICD-9: 270-279] | Approved | [1] | |
| Company |
Genzyme
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| Structure |
 |
Download2D MOL |
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| Formula |
C50H78N4O14
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| Canonical SMILES |
CCCCCCCC(=O)NC(CN1CCCC1)C(C2=CC3=C(C=C2)OCCO3)O.CCCCCCCC(=O)NC(CN1CCCC1)C(C2=CC3=C(C=C2)OCCO3)O.C(C(C(=O)O)O)(C(=O)O)O
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| InChI |
1S/2C23H36N2O4.C4H6O6/c2*1-2-3-4-5-6-9-22(26)24-19(17-25-12-7-8-13-25)23(27)18-10-11-20-21(16-18)29-15-14-28-20;5-1(3(7)8)2(6)4(9)10/h2*10-11,16,19,23,27H,2-9,12-15,17H2,1H3,(H,24,26);1-2,5-6H,(H,7,8)(H,9,10)/t2*19-,23-;1-,2-/m111/s1
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| InChIKey |
KUBARPMUNHKBIQ-VTHUDJRQSA-N
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| CAS Number |
CAS 928659-70-5
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| PubChem Compound ID | ||||
| PubChem Substance ID | ||||
| ChEBI ID |
CHEBI:83353
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| ADReCS Drug ID | BADD_D00757 | |||
| SuperDrug ATC ID |
A16AX10
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Ceramide glucosyltransferase (UGCG) | Target Info | Modulator | [1] |
| KEGG Pathway | Sphingolipid metabolism | |||
| Metabolic pathways | ||||
| NetPath Pathway | TGF_beta_Receptor Signaling Pathway | |||
| Pathwhiz Pathway | Sphingolipid Metabolism | |||
| Pathway Interaction Database | IL2 signaling events mediated by PI3K | |||
| Reactome | Glycosphingolipid metabolism | |||
| WikiPathways | Sphingolipid metabolism | |||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | 2014 FDA drug approvals. Nat Rev Drug Discov. 2015 Feb;14(2):77-81. | |||
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