Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0J7ML
|
|||
| Former ID |
DIB001624
|
|||
| Drug Name |
D-20133
|
|||
| Synonyms |
OMPEP; octadecyl-(2-(N-methylpiperidino)ethyl)phosphate; 146764-26-3; D 20133; 1-(2-((Hydroxy(octadecyloxy)phosphinyl)oxy)ethyl)-1-methylpiperidinium inner salt; Piperidinium, 1-(2-((hydroxy(octadecyloxy)phosphinyl)oxy)ethyl)-1-methyl-, inner salt; SCHEMBL2293548; AC1L31K0; DTXSID90163471; LS-116681; 2-(1-methylpiperidin-1-ium-1-yl)ethyl octadecyl phosphate
Click to Show/Hide
|
|||
| Drug Type |
Small molecular drug
|
|||
| Indication | Solid tumour/cancer [ICD-11: 2A00-2F9Z; ICD-10: C76-C80; ICD-9: 140-229] | Phase 1 | [1] | |
| Company |
ASTA Medica AG
|
|||
| Structure |
 |
Download2D MOL
|
||
| Formula |
C26H55NO4P+
|
|||
| Canonical SMILES |
CCCCCCCCCCCCCCCCCCOP(=O)(O)OCC[N+]1(CCCCC1)C
|
|||
| InChI |
1S/C26H54NO4P/c1-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-21-25-30-32(28,29)31-26-24-27(2)22-19-18-20-23-27/h3-26H2,1-2H3/p+1
|
|||
| InChIKey |
CUQJLYFFQBHUGW-UHFFFAOYSA-O
|
|||
| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Phospholipase C (PLC) | Target Info | Inhibitor | [2] |
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Antineoplastic activity and tolerability of a novel heterocyclic alkylphospholipid, D-20133. Cancer Chemother Pharmacol. 1993;32(6):437-44. | |||
| REF 2 | Novel Inhibitors of AKT: Assessment of a Different Approach Targeting the Pleckstrin Homology Domain. Curr Med Chem. 2011; 18(18): 2727-2742. | |||
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.