Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0J5VR
|
|||
| Former ID |
DNCL003461
|
|||
| Drug Name |
Idelalisib
|
|||
| Synonyms |
Idelalisib; 870281-82-6; CAL-101; Zydelig; GS-1101; CAL101; CAL 101; (S)-2-(1-((9H-Purin-6-yl)amino)propyl)-5-fluoro-3-phenylquinazolin-4(3H)-one; UNII-YG57I8T5M0; CAL-101 (Idelalisib, GS-1101); YG57I8T5M0; CHEMBL2216870; CHEBI:82701; 5-Fluoro-3-phenyl-2-((S)-1-(9H-purin-6-ylamino)-propyl)-3H-quinazolin-4-one; AK145603; Idelalisib; CAL-101; (S)-2-(1-(9H-purin-6-ylamino)propyl)-5-fluoro-3-phenylquinazolin-4(3H)-one; 1146702-54-6; 5-FLUORO-3-PHENYL-2-[(1S)-1-(9H-PURIN-6-YLAMINO)PROPYL]-4(3H)-QUINAZOLINONE
Click to Show/Hide
|
|||
| Drug Type |
Small molecular drug
|
|||
| Indication | Chronic lymphocytic leukaemia [ICD-11: 2A82.0; ICD-10: C83.0, C91.1] | Approved | [1], [2] | |
| Company |
Gilead Sciences
|
|||
| Structure |
 |
Download2D MOL
|
||
| Formula |
C22H18FN7O
|
|||
| Canonical SMILES |
CCC(C1=NC2=C(C(=CC=C2)F)C(=O)N1C3=CC=CC=C3)NC4=NC=NC5=C4NC=N5
|
|||
| InChI |
1S/C22H18FN7O/c1-2-15(28-20-18-19(25-11-24-18)26-12-27-20)21-29-16-10-6-9-14(23)17(16)22(31)30(21)13-7-4-3-5-8-13/h3-12,15H,2H2,1H3,(H2,24,25,26,27,28)/t15-/m0/s1
|
|||
| InChIKey |
IFSDAJWBUCMOAH-HNNXBMFYSA-N
|
|||
| CAS Number |
CAS 870281-82-6
|
|||
| PubChem Compound ID | ||||
| PubChem Substance ID |
16728852, 78058152, 124360767, 124757878, 125164680, 135294860, 136023431, 136340110, 136350004, 136367521, 136368015, 137275917, 141870606, 144115773, 152258425, 160647261, 160778577, 162011391, 162038002, 162202617, 163315619, 163352092, 163642790, 163908064, 164043527, 164193919, 170497648, 170501514, 172650954, 172913174, 174531110, 177749172, 178103352, 184826685, 198954688, 198994003, 215785737, 223447422, 223471406, 223573729, 223705059, 224220340, 225144930, 226689936, 248327652, 249737291, 249814532, 249828711, 250183703, 250220450
|
|||
| ChEBI ID |
CHEBI:82701
|
|||
| ADReCS Drug ID | BADD_D01130 | |||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 6741). | |||
| REF 2 | 2014 FDA drug approvals. Nat Rev Drug Discov. 2015 Feb;14(2):77-81. | |||
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.