Drug Information
Drug General Information | Top | |||
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Drug ID |
D0J4CL
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Drug Name |
PMID29649907-Compound-19
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Drug Type |
Small molecular drug
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Company |
SUNSHINE LAKE PHARMA CO., LTD
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Structure |
Download2D MOL |
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Formula |
C27H19Cl2NO7S
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Canonical SMILES |
C1CC1C2=C(C(=NO2)C3=C(C=CC=C3Cl)Cl)COC4=CC5=C(C=C4)OC6=C(CS5(=O)=O)C=CC(=C6)C(=O)O
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InChI |
1S/C27H19Cl2NO7S/c28-19-2-1-3-20(29)24(19)25-18(26(37-30-25)14-4-5-14)12-35-17-8-9-21-23(11-17)38(33,34)13-16-7-6-15(27(31)32)10-22(16)36-21/h1-3,6-11,14H,4-5,12-13H2,(H,31,32)
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InChIKey |
LTDMSLKNDBRACZ-UHFFFAOYSA-N
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PubChem Compound ID |
Target and Pathway | Top | |||
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Target(s) | Farnesoid X-activated receptor (FXR) | Target Info | Agonist | [1] |
Target's Patent Info | Farnesoid X-activated receptor (FXR) | Target's Patent Info | [1] | |
KEGG Pathway | Bile secretion | |||
Pathway Interaction Database | RXR and RAR heterodimerization with other nuclear receptor | |||
Reactome | Recycling of bile acids and salts | |||
PPARA activates gene expression | ||||
Endogenous sterols | ||||
WikiPathways | Nuclear Receptors in Lipid Metabolism and Toxicity | |||
Nuclear Receptors Meta-Pathway | ||||
Farnesoid X Receptor Pathway | ||||
Drug Induction of Bile Acid Pathway |
References | Top | |||
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REF 1 | Farnesoid X receptor modulators 2014-present: a patent review.Expert Opin Ther Pat. 2018 May;28(5):351-364. |
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