Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0J0RV
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| Former ID |
DCL000552
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| Drug Name |
Larotaxel
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| Synonyms |
Benzenepropanoic acid; PNU 100940; XRP 9881; XRP9881
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| Drug Type |
Small molecular drug
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| Indication | Bladder cancer [ICD-11: 2C94] | Discontinued in Phase 3 | [1] | |
| Pancreatic cancer [ICD-11: 2C10] | Discontinued in Phase 3 | [1] | ||
| Company |
Sanofi-Aventis
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| Structure |
 |
Download2D MOL |
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| Formula |
C45H53NO14
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| Canonical SMILES |
CC1=C2C(C(=O)C34CC3CC5C(C4C(C(C2(C)C)(CC1OC(=O)C(C(C6=CC=CC=C6)NC(=O)OC(C)(C)C)O)O)OC(=O)C7=CC=CC=C7)(CO5)OC(=O)C)OC(=O)C
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| InChI |
1S/C45H53NO14/c1-23-29(57-39(52)33(49)32(26-15-11-9-12-16-26)46-40(53)60-41(4,5)6)21-45(54)37(58-38(51)27-17-13-10-14-18-27)35-43(36(50)34(56-24(2)47)31(23)42(45,7)8)20-28(43)19-30-44(35,22-55-30)59-25(3)48/h9-18,28-30,32-35,37,49,54H,19-22H2,1-8H3,(H,46,53)/t28-,29+,30-,32+,33-,34-,35+,37+,43-,44+,45-/m1/s1
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| InChIKey |
DXOJIXGRFSHVKA-BZVZGCBYSA-N
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| CAS Number |
CAS 156294-36-9
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| PubChem Compound ID | ||||
| PubChem Substance ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Tubulin (TUB) | Target Info | Inhibitor | [2] |
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800010227) | |||
| REF 2 | Pharma & Vaccines. Product Development Pipeline. April 29 2009. | |||
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