Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0J0MK
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| Former ID |
DIB012738
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| Drug Name |
JTT-608
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| Synonyms |
Trans-4-(4-Methylcyclohexyl)-4-oxobutanoic acid
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| Drug Type |
Small molecular drug
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| Indication | Diabetic complication [ICD-11: 5A2Y; ICD-9: 253.5, 588.1] | Terminated | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C11H18O3
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| Canonical SMILES |
CC1CCC(CC1)C(=O)CCC(=O)O
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| InChI |
1S/C11H18O3/c1-8-2-4-9(5-3-8)10(12)6-7-11(13)14/h8-9H,2-7H2,1H3,(H,13,14)
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| InChIKey |
JOWMTYWOBJALGB-UHFFFAOYSA-N
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| CAS Number |
CAS 195137-72-5
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| PubChem Compound ID | ||||
| PubChem Substance ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Phosphodiesterase (PDE) | Target Info | Inhibitor | [2] |
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800011585) | |||
| REF 2 | JTT-608 controls blood glucose by enhancement of glucose-stimulated insulin secretion in normal and diabetes mellitus rats. Eur J Pharmacol. 1999 Feb 12;367(1):91-9. | |||
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