Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0J0CB
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| Former ID |
DNC000433
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| Drug Name |
Cilostamide
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| Synonyms |
cilostamide; 68550-75-4; ciloalamide; OPC 3689; Cilostamide [INN]; N-Cyclohexyl-N-methyl-4-(1,2-dihydro-2-oxo-6-quinolyloxy)butyramide; Cilostamidum [INN-Latin]; Cilostamida [INN-Spanish]; UNII-45S5605Q18; OPC 3869; CHEMBL34431; NCGC00015269-03; N-cyclohexyl-N-methyl-4-[(2-oxo-1H-quinolin-6-yl)oxy]butanamide; 45S5605Q18; Butanamide, N-cyclohexyl-4-((1,2-dihydro-2-oxo-6-quinolinyl)oxy)-N-methyl-; N-Cyclohexyl-N-methyl-4-((2-oxo-1,2-dihydroquinolin-6-yl)oxy)butanamide; DSSTox_RID_80698; DSSTox_CID_25140; DSSTox_GSID_45140
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
 |
Download2D MOL |
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| Formula |
C20H26N2O3
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| Canonical SMILES |
CN(C1CCCCC1)C(=O)CCCOC2=CC3=C(C=C2)NC(=O)C=C3
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| InChI |
1S/C20H26N2O3/c1-22(16-6-3-2-4-7-16)20(24)8-5-13-25-17-10-11-18-15(14-17)9-12-19(23)21-18/h9-12,14,16H,2-8,13H2,1H3,(H,21,23)
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| InChIKey |
UIAYVIIHMORPSJ-UHFFFAOYSA-N
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| CAS Number |
CAS 68550-75-4
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| PubChem Compound ID | ||||
| PubChem Substance ID |
6897915, 8151778, 11110986, 11113785, 15026182, 17404851, 24278337, 26758471, 29221908, 46515603, 47885519, 48110558, 50065070, 50104638, 50104639, 53777394, 57321434, 76679546, 85084873, 85230981, 85787160, 90341615, 91703610, 92303622, 92309182, 103210093, 103840864, 103931591, 104301508, 117568194, 121361002, 121379816, 124749599, 124879745, 124879746, 125666116, 129371308, 134222325, 134339859, 135026865, 135698153, 142493401, 144203670, 162022771, 162093847, 162313005, 163564242, 163688365, 165222621, 165222688
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| ChEBI ID |
CHEBI:92503
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Phosphodiesterase 3 (PDE3) | Target Info | Inhibitor | [2] |
| References | Top | |||
|---|---|---|---|---|
| REF 1 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 5167). | |||
| REF 2 | Phosphodiesterase 3 as a potential target for therapy of malignant tumors in the submandibular gland. Anticancer Drugs. 2001 Jan;12(1):79-83. | |||
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