Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0I9PA
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| Former ID |
DNC009635
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| Drug Name |
3-(2,3-Dihydro-1,4-benzodioxin-6-yl)pyridine
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| Synonyms |
CHEMBL462092; 1092522-84-3; 3-(2,3-Dihydrobenzo[b][1,4]dioxin-6-yl)pyridine; 3-(2,3-Dihydro-1,4-benzodioxin-6-yl)pyridine; 3-(2,3-Dihydro-benzo[1,4]dioxin-6-yl)-pyridine; ZINC40873967; BDBM50273702
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C13H11NO2
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| Canonical SMILES |
C1COC2=C(O1)C=CC(=C2)C3=CN=CC=C3
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| InChI |
1S/C13H11NO2/c1-2-11(9-14-5-1)10-3-4-12-13(8-10)16-7-6-15-12/h1-5,8-9H,6-7H2
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| InChIKey |
WBKBSDQNOSGKCC-UHFFFAOYSA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Steroid 11-beta-hydroxylase (CYP11B1) | Target Info | Inhibitor | [1] |
| BioCyc | Superpathway of steroid hormone biosynthesis | |||
| Glucocorticoid biosynthesis | ||||
| Mineralocorticoid biosynthesis | ||||
| KEGG Pathway | Steroid hormone biosynthesis | |||
| Metabolic pathways | ||||
| Pathwhiz Pathway | Steroidogenesis | |||
| Reactome | Glucocorticoid biosynthesis | |||
| Endogenous sterols | ||||
| WikiPathways | Metapathway biotransformation | |||
| Oxidation by Cytochrome P450 | ||||
| Metabolism of steroid hormones and vitamin D | ||||
| Corticotropin-releasing hormone | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | In vivo active aldosterone synthase inhibitors with improved selectivity: lead optimization providing a series of pyridine substituted 3,4-dihydro-... J Med Chem. 2008 Dec 25;51(24):8077-87. | |||
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