Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0I8PQ
|
|||
| Former ID |
DNC004390
|
|||
| Drug Name |
S-(N-ethyl-N-hydroxycarbamoyl)glutathione
|
|||
| Synonyms |
CHEMBL128867; S-(N-ethyl-N-hydroxycarbamoyl)glutathione; SCHEMBL3287492; BDBM50092832
Click to Show/Hide
|
|||
| Drug Type |
Small molecular drug
|
|||
| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
 |
Download2D MOL |
||
| Formula |
C13H22N4O8S
|
|||
| Canonical SMILES |
CCN(C(=O)SCC(C(=O)NCC(=O)O)NC(=O)CCC(C(=O)O)N)O
|
|||
| InChI |
1S/C13H22N4O8S/c1-2-17(25)13(24)26-6-8(11(21)15-5-10(19)20)16-9(18)4-3-7(14)12(22)23/h7-8,25H,2-6,14H2,1H3,(H,15,21)(H,16,18)(H,19,20)(H,22,23)/t7-,8-/m0/s1
|
|||
| InChIKey |
WQKIQOZTTDZDHN-YUMQZZPRSA-N
|
|||
| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Lactoylglutathione lyase (GLO1) | Target Info | Inhibitor | [1] |
| BioCyc | Methylglyoxal degradation I | |||
| KEGG Pathway | Pyruvate metabolism | |||
| NetPath Pathway | TCR Signaling Pathway | |||
| Pathwhiz Pathway | Pyruvaldehyde Degradation | |||
| Pyruvate Metabolism | ||||
| Reactome | Pyruvate metabolism | |||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Role of hydrophobic interactions in binding S-(N-aryl/alkyl-N-hydroxycarbamoyl)glutathiones to the active site of the antitumor target enzyme glyoxalase I. J Med Chem. 2000 Oct 19;43(21):3981-6. | |||
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.