Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D0I4OV
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| Former ID |
DNC010113
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| Drug Name |
(4-(thiophen-2-yl)phenyl)methanamine
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| Synonyms |
4-(2-Thienyl)benzylamine; 4-(2-THIENYL)BENZYLAMINE; 203436-48-0; 1-(4-thiophen-2-ylphenyl)methanamine; [4-(Thiophen-2-Yl)Phenyl]Methanamine; CHEMBL539640; Benzenemethanamine,4-(2-thienyl)-; Benzenemethanamine, 4-(2-thienyl)-; SDCCGMLS-0065961P001; AC1MCQW2; AC1Q53XJ; 4-(2-thienyl) benzylamine; 4-(Thien-2-yl)benzylamine; SCHEMBL112455; CTK4E3973; DTXSID90379994; YKNLMMDEWQZCLJ-UHFFFAOYSA-N; MolPort-000-142-431; HMS3604G04; ZINC158702; (4-(2-thienyl)phenyl)methylamine; (4-thiophen-2-ylphenyl)methanamine; SBB091000
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1], [2] | |
| Structure |
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Download2D MOL |
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| Formula |
C11H11NS
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| Canonical SMILES |
C1=CSC(=C1)C2=CC=C(C=C2)CN
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| InChI |
1S/C11H11NS/c12-8-9-3-5-10(6-4-9)11-2-1-7-13-11/h1-7H,8,12H2
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| InChIKey |
YKNLMMDEWQZCLJ-UHFFFAOYSA-N
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| CAS Number |
CAS 203436-48-0
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Leukotriene A-4 hydrolase (LTA4H) | Target Info | Inhibitor | [1], [2] |
| BioCyc | Leukotriene biosynthesis | |||
| KEGG Pathway | Arachidonic acid metabolism | |||
| Metabolic pathways | ||||
| Pathwhiz Pathway | Arachidonic Acid Metabolism | |||
| WikiPathways | Arachidonic acid metabolism | |||
| Eicosanoid Synthesis | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. | |||
| REF 2 | Discovery of 4-[(2S)-2-{[4-(4-chlorophenoxy)phenoxy]methyl}-1-pyrrolidinyl]butanoic acid (DG-051) as a novel leukotriene A4 hydrolase inhibitor of ... J Med Chem. 2010 Jan 28;53(2):573-85. | |||
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