Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0HS3M
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| Former ID |
DNC013569
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| Drug Name |
1-(1-(pyrazin-2-yl)ethylidene)thiosemicarbazide
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| Synonyms |
CHEMBL401556; AC1NT9J5; 142564-78-1; BDBM50376205; ZINC26974934; AKOS014545779; 1-(2-Pyrazinyl)ethanone thiosemicarbazone
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C7H9N5S
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| Canonical SMILES |
CC(=NNC(=S)N)C1=NC=CN=C1
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| InChI |
1S/C7H9N5S/c1-5(11-12-7(8)13)6-4-9-2-3-10-6/h2-4H,1H3,(H3,8,12,13)/b11-5-
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| InChIKey |
LNRWBLGPWCJQEM-WZUFQYTHSA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Tyrosinase (TYR) | Target Info | Inhibitor | [1] |
| BioCyc | (S)-reticuline biosynthesis | |||
| Eumelanin biosynthesis | ||||
| L-dopachrome biosynthesis | ||||
| KEGG Pathway | Tyrosine metabolism | |||
| Riboflavin metabolism | ||||
| Metabolic pathways | ||||
| Melanogenesis | ||||
| Pathwhiz Pathway | Riboflavin Metabolism | |||
| Tyrosine Metabolism | ||||
| WikiPathways | Dopamine metabolism | |||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | 1-(1-Arylethylidene)thiosemicarbazide derivatives: a new class of tyrosinase inhibitors. Bioorg Med Chem. 2008 Feb 1;16(3):1096-102. | |||
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