Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0HR1V
|
|||
| Former ID |
DIB018596
|
|||
| Drug Name |
3-iodothyronamine
|
|||
| Synonyms |
CHEMBL201002; 3'-iodothyronamine; 3''-iodothyronamine; GTPL2145; SCHEMBL13886595; BDBM50181801; 4-[4-(2-aminoethyl)phenoxy]-2-iodophenol
Click to Show/Hide
|
|||
| Drug Type |
Small molecular drug
|
|||
| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
 |
Download2D MOL |
||
| Formula |
C14H14INO2
|
|||
| Canonical SMILES |
C1=CC(=CC=C1O)OC2=C(C=C(C=C2)CCN)I
|
|||
| InChI |
1S/C14H14INO2/c15-13-9-10(7-8-16)1-6-14(13)18-12-4-2-11(17)3-5-12/h1-6,9,17H,7-8,16H2
|
|||
| InChIKey |
XIINYOJWNGOUPF-UHFFFAOYSA-N
|
|||
| CAS Number |
CAS 712349-95-6
|
|||
| PubChem Compound ID | ||||
| PubChem Substance ID | ||||
| ChEBI ID |
CHEBI:89700
|
|||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Trace amine-associated receptor-1 (TAAR1) | Target Info | Agonist | [2] |
| KEGG Pathway | Neuroactive ligand-receptor interaction | |||
| Reactome | G alpha (s) signalling events | |||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 2145). | |||
| REF 2 | Exploring the structure-activity relationship of the ethylamine portion of 3-iodothyronamine for rat and mouse trace amine-associated receptor 1. J Med Chem. 2007 Jun 14;50(12):2787-98. | |||
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.