Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0HO8V
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| Drug Name |
Pyrrolo-pyrrolone derivative 4
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| Synonyms |
PMID26924192-Compound-37
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| Drug Type |
Small molecular drug
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| Company |
NOVARTIS AG [CHBLANK JUTTA [CHBOLD GUIDO [CHBORDAS VINCENT [CHCOTESTA SIMONA [CHGUAGNANO VITO [CHR EGER HEINRICH [CHVAUPEL ANDREA [CH]
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| Structure |
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Download2D MOL |
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| Formula |
C22H19ClF2N8O2
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| Canonical SMILES |
CC1=CC(=NN2C1=NN=C2C(F)F)N3C(C4=C(C3=O)C(=CN4C)NC(=O)NC)C5=CC=C(C=C5)Cl
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| InChI |
1S/C22H19ClF2N8O2/c1-10-8-14(30-33-19(10)28-29-20(33)18(24)25)32-16(11-4-6-12(23)7-5-11)17-15(21(32)34)13(9-31(17)3)27-22(35)26-2/h4-9,16,18H,1-3H3,(H2,26,27,35)
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| InChIKey |
RNLAJPMWXHNSOJ-UHFFFAOYSA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Bromodomain-containing protein 4 (BRD4) | Target Info | Inhibitor | [1] |
| Target's Patent Info | Bromodomain-containing protein 4 (BRD4) | Target's Patent Info | [1] | |
| WikiPathways | Chemical Compounds to monitor Proteins | |||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | BET inhibitors in cancer therapeutics: a patent review.Expert Opin Ther Pat. 2016;26(4):505-22. | |||
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