Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0HM5J
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| Drug Name |
Brensocatib
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| Synonyms |
AZD7986; AZD-7986; UNII-25CG88L0BB; 25CG88L0BB; INS1007; INS-1007; AZD 7986
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| Drug Type |
Small molecular drug
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| Indication | Coronavirus Disease 2019 (COVID-19) [ICD-11: 1D6Y] | Preclinical | [1] | |
| Therapeutic Class |
Antiviral Agents
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| Structure |
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Download2D MOL |
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| Formula |
C23H24N4O4
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| Canonical SMILES |
CN1C2=C(C=CC(=C2)C3=CC=C(C=C3)CC(C#N)NC(=O)C4CNCCCO4)OC1=O
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| InChI |
1S/C23H24N4O4/c1-27-19-12-17(7-8-20(19)31-23(27)29)16-5-3-15(4-6-16)11-18(13-24)26-22(28)21-14-25-9-2-10-30-21/h3-8,12,18,21,25H,2,9-11,14H2,1H3,(H,26,28)/t18-,21-/m0/s1
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| InChIKey |
AEXFXNFMSAAELR-RXVVDRJESA-N
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| CAS Number |
CAS 1802148-05-5
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | HUMAN dipeptidyl peptidase 1 (CTSC) | Target Info | Inhibitor | [1] |
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Brensocatib (Formerly INS1007) to be Studied in Patients with Severe COVID-19 in Investigator-Initiated Trial. Apr 23, 2020. | |||
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