Drug Information
Drug General Information | Top | |||
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Drug ID |
D0HH1O
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Drug Name |
PMID25522065-Compound-14
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Drug Type |
Small molecular drug
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Company |
BOEHRINGER INGELHEIM INTERNATIONAL GMBH
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Structure |
Download2D MOL |
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Formula |
C24H26N2O3
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Canonical SMILES |
CC1=C(C=CC(=C1)CN(C)C)C(=O)CN2C=CC(=CC2=O)OCC3=CC=CC=C3
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InChI |
1S/C24H26N2O3/c1-18-13-20(15-25(2)3)9-10-22(18)23(27)16-26-12-11-21(14-24(26)28)29-17-19-7-5-4-6-8-19/h4-14H,15-17H2,1-3H3
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InChIKey |
QONJYPHKWHUJOW-UHFFFAOYSA-N
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PubChem Compound ID |
Target and Pathway | Top | |||
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Target(s) | Melanin-concentrating hormone receptor 1 (MCHR1) | Target Info | Antagonist | [1] |
Target's Patent Info | Melanin-concentrating hormone receptor 1 (MCHR1) | Target's Patent Info | [1] | |
KEGG Pathway | Neuroactive ligand-receptor interaction | |||
Reactome | Peptide ligand-binding receptors | |||
G alpha (q) signalling events | ||||
G alpha (i) signalling events | ||||
WikiPathways | GPCRs, Class A Rhodopsin-like | |||
Gastrin-CREB signalling pathway via PKC and MAPK | ||||
GPCR ligand binding | ||||
GPCR downstream signaling |
References | Top | |||
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REF 1 | Novel MCH1 receptor antagonists: a patent review.Expert Opin Ther Pat. 2015 Feb;25(2):193-207. |
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