Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0HF0R
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| Drug Name |
Aminopyrimidine derivative 4
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| Synonyms |
PMID25656651-Compound-13
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| Drug Type |
Small molecular drug
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| Company |
VERTEX PHARMACEUTICALS INCORPORATED
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| Structure |
 |
Download2D MOL |
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| Formula |
C28H32F3N9S
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| Canonical SMILES |
CC1=CC(=NN1)NC2=CC(=NC(=N2)SC3=CC4=C(C=C3)N=C(C=C4)C(F)(F)F)N5CCN(CC5)C6CCN(CC6)C
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| InChI |
1S/C28H32F3N9S/c1-18-15-25(37-36-18)33-24-17-26(40-13-11-39(12-14-40)20-7-9-38(2)10-8-20)35-27(34-24)41-21-4-5-22-19(16-21)3-6-23(32-22)28(29,30)31/h3-6,15-17,20H,7-14H2,1-2H3,(H2,33,34,35,36,37)
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| InChIKey |
CBMIRUJKKBNHQV-UHFFFAOYSA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Fusion protein Bcr-Abl (Bcr-Abl) | Target Info | Inhibitor | [1] |
| Target's Patent Info | Fusion protein Bcr-Abl (Bcr-Abl) | Target's Patent Info | [1] | |
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Bcr-Abl tyrosine kinase inhibitors: a patent review.Expert Opin Ther Pat. 2015 Apr;25(4):397-412. | |||
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