Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0H9YO
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| Former ID |
DIB012850
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| Drug Name |
FLUASTERONE
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| Synonyms |
HE-2500; 16alpha-Fluoroandrost-5-en-17-one; 8354
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| Drug Type |
Small molecular drug
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| Indication | Arthritis [ICD-11: FA20] | Phase 2 | [1] | |
| Company |
Aeson Therapeutics
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| Structure |
 |
Download2D MOL |
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| Formula |
C19H27FO
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| Canonical SMILES |
CC12CCCCC1=CCC3C2CCC4(C3CC(C4=O)F)C
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| InChI |
1S/C19H27FO/c1-18-9-4-3-5-12(18)6-7-13-14(18)8-10-19(2)15(13)11-16(20)17(19)21/h6,13-16H,3-5,7-11H2,1-2H3/t13-,14+,15+,16-,18+,19+/m1/s1
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| InChIKey |
VHZXNQKVFDBFIK-NBBHSKLNSA-N
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| CAS Number |
CAS 112859-71-9
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| PubChem Compound ID | ||||
| PubChem Substance ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Nuclear receptor unspecific (NR) | Target Info | Modulator | [2] |
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Clinical pipeline report, company report or official report of Aeson Therapeutics. Oct 28, 2002. | |||
| REF 2 | Dehydroepiandrosterone activates endothelial cell nitric-oxide synthase by a specific plasma membrane receptor coupled to Galpha(i2,3). J Biol Chem. 2002 Jun 14;277(24):21379-88. | |||
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