Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0H9AU
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| Drug Name |
PMID25776143-Compound-8
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| Drug Type |
Small molecular drug
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| Company |
Ferring BV
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| Structure |
 |
Download2D MOL |
||
| Formula |
C24H24ClN5O2
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| Canonical SMILES |
CC1=C(C=CC(=C1)C(=O)N2CC3=C(NC4=C2C=CC(=C4)Cl)N(N=C3)C)CNC(=O)C5CC5
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| InChI |
1S/C24H24ClN5O2/c1-14-9-16(5-6-17(14)11-26-23(31)15-3-4-15)24(32)30-13-18-12-27-29(2)22(18)28-20-10-19(25)7-8-21(20)30/h5-10,12,15,28H,3-4,11,13H2,1-2H3,(H,26,31)
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| InChIKey |
DZLYFDUKRUYUIP-UHFFFAOYSA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Vasopressin V1a receptor (V1AR) | Target Info | Antagonist | [1] |
| Target's Patent Info | Vasopressin V1a receptor (V1AR) | Target's Patent Info | [1] | |
| KEGG Pathway | Calcium signaling pathway | |||
| Neuroactive ligand-receptor interaction | ||||
| Vascular smooth muscle contraction | ||||
| Reactome | Vasopressin-like receptors | |||
| G alpha (q) signalling events | ||||
| WikiPathways | GPCRs, Class A Rhodopsin-like | |||
| Gastrin-CREB signalling pathway via PKC and MAPK | ||||
| Peptide GPCRs | ||||
| GPCR ligand binding | ||||
| GPCR downstream signaling | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Vasopressin V1a and V1b receptor modulators: a patent review (2012 - 2014).Expert Opin Ther Pat. 2015 Jun;25(6):711-22. | |||
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