Drug Information
Drug General Information | Top | |||
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Drug ID |
D0H7KP
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Former ID |
DNC014547
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Drug Name |
(3-Amino-1-hydroxy-propyl)-methyl-phosphinic acid
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Synonyms |
SCHEMBL341289
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Drug Type |
Small molecular drug
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Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
Structure |
Download2D MOL |
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Formula |
C4H11NO3P+
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Canonical SMILES |
C[P+](C(=O)CCN)(O)O
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InChI |
1S/C4H11NO3P/c1-9(7,8)4(6)2-3-5/h7-8H,2-3,5H2,1H3/q+1
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InChIKey |
XRHWOLGPXAOKPF-UHFFFAOYSA-N
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PubChem Compound ID |
Target and Pathway | Top | |||
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Target(s) | Gamma-aminobutyric acid B receptor (GABBR) | Target Info | Inhibitor | [1] |
KEGG Pathway | cAMP signaling pathway | |||
Neuroactive ligand-receptor interaction | ||||
GABAergic synapse | ||||
Estrogen signaling pathway | ||||
Morphine addiction | ||||
Reactome | Activation of G protein gated Potassium channels | |||
G alpha (i) signalling events | ||||
Class C/3 (Metabotropic glutamate/pheromone receptors) | ||||
Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits | ||||
WikiPathways | GPCRs, Class C Metabotropic glutamate, pheromone | |||
Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell | ||||
Potassium Channels | ||||
GPCR ligand binding | ||||
GPCR downstream signaling |
References | Top | |||
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REF 1 | Phosphinic acid analogues of GABA. 1. New potent and selective GABAB agonists. J Med Chem. 1995 Aug 18;38(17):3297-312. |
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