Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0H7JE
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| Former ID |
DNC001237
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| Drug Name |
RS-100302
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| Synonyms |
UNII-XX514BJ1XW; XX514BJ1XW; 120788-07-0; Sulopenem [USAN:INN]; AC1OCF0J; SCHEMBL73397; FLSUCZWOEMTFAQ-IIOOQZKLSA-N; (5R,6S)-6-((1R)-1-Hydroxyethyl)-7-oxo-3-(((3S)-tetrahydro-3-thienyl)thio)-4-thia-1-azabicyclo(3.2.0)hept-2-ene-2-carboxylic acid, (R)-S-oxide; (5R,6S)-6-[(1R)-1-hydroxyethyl]-7-oxo-3-[(3S)-1-oxothiolan-3-yl]sulfanyl-4-thia-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid; 4-Thia-1-azabicyclo(3.2.0)hept-2-ene-2-carboxylic acid, 6-(1-hydroxyethyl)-7-oxo-3-((tetrahydro-3-thie
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| Drug Type |
Small molecular drug
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| Indication | Atrial fibrillation [ICD-11: BC81.3; ICD-10: I48] | Investigative | [1] | |
| Company |
Roche
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| Structure |
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Download2D MOL |
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| Formula |
C19H28ClN3O5S
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| Canonical SMILES |
CS(=O)(=O)NCCN1CCC(CC1)CCC(=O)C2=CC(=C(C3=C2OCCO3)N)Cl
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| InChI |
1S/C19H28ClN3O5S/c1-29(25,26)22-6-9-23-7-4-13(5-8-23)2-3-16(24)14-12-15(20)17(21)19-18(14)27-10-11-28-19/h12-13,22H,2-11,21H2,1H3
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| InChIKey |
NBUGBCTWXCXBQD-UHFFFAOYSA-N
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| CAS Number |
CAS 219757-90-1
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| PubChem Compound ID | ||||
| PubChem Substance ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Voltage-gated potassium channel Kv1.5 (KCNA5) | Target Info | Blocker | [1] |
| Pathwhiz Pathway | Muscle/Heart Contraction | |||
| Reactome | Voltage gated Potassium channels | |||
| WikiPathways | Potassium Channels | |||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | New antiarrhythmic agents for atrial fibrillation and atrial flutter. Expert Opin Emerg Drugs. 2005 May;10(2):311-22. | |||
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