Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D0H7DQ
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| Former ID |
DIB020733
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| Drug Name |
K00248
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| Synonyms |
PKCbeta Inhibitor; 257879-35-9; K00248; CHEMBL366266; 3-(1-(3-Imidazol-1-ylpropyl)-1H-indol-3-yl)-4-anilino-1H-pyrrole-2,5-dione; PKC Inhibitor; AC1O4WCS; SCHEMBL7841474; GTPL6025; CHEBI:94140; CTK8F0351; DTXSID20423555; HMS3229K09; BDBM50153461; IN1136; CCG-206785; RT-015068; J-016132; BRD-K89687904-001-01-8; 3-anilino-4-[1-(3-imidazol-1-ylpropyl)indol-3-yl]pyrrole-2,5-dione; 3-[1-[3-(1H-Imidazole-1-yl)propyl]-1H-indole-3-yl]-4-anilino-1H-pyrrole-2,5-dione
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL
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| Formula |
C24H21N5O2
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| Canonical SMILES |
C1=CC=C(C=C1)NC2=C(C(=O)NC2=O)C3=CN(C4=CC=CC=C43)CCCN5C=CN=C5
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| InChI |
1S/C24H21N5O2/c30-23-21(22(24(31)27-23)26-17-7-2-1-3-8-17)19-15-29(20-10-5-4-9-18(19)20)13-6-12-28-14-11-25-16-28/h1-5,7-11,14-16H,6,12-13H2,(H2,26,27,30,31)
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| InChIKey |
KIWODJBCHRADND-UHFFFAOYSA-N
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| CAS Number |
CAS 257879-35-9
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| PubChem Compound ID | ||||
| PubChem Substance ID | ||||
| ChEBI ID |
CHEBI:94140
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| References | Top | |||
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| REF 1 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 6025). | |||
| REF 2 | Synthesis of anilino-monoindolylmaleimides as potent and selective PKCbeta inhibitors. Bioorg Med Chem Lett. 2004 Oct 18;14(20):5171-4. | |||
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