Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0H6WG
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| Former ID |
DNC009516
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| Drug Name |
1-(2-mercaptoethyl)-3-(m-tolylsulfonyl)urea
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| Synonyms |
CHEMBL459135; 1-(2-mercaptoethyl)-3-(m-tolylsulfonyl)urea
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C10H14N2O3S2
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| Canonical SMILES |
CC1=CC(=CC=C1)S(=O)(=O)NC(=O)NCCS
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| InChI |
1S/C10H14N2O3S2/c1-8-3-2-4-9(7-8)17(14,15)12-10(13)11-5-6-16/h2-4,7,16H,5-6H2,1H3,(H2,11,12,13)
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| InChIKey |
CALOUQXNCIXXTN-UHFFFAOYSA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Fructose-1,6-bisphosphatase (FBP) | Target Info | Inhibitor | [1] |
| BioCyc | Gluconeogenesis | |||
| KEGG Pathway | Glycolysis / Gluconeogenesis | |||
| Pentose phosphate pathway | ||||
| Fructose and mannose metabolism | ||||
| Metabolic pathways | ||||
| Biosynthesis of antibiotics | ||||
| Carbon metabolism | ||||
| AMPK signaling pathway | ||||
| Insulin signaling pathway | ||||
| Glucagon signaling pathway | ||||
| Pathwhiz Pathway | Fructose and Mannose Degradation | |||
| Pentose Phosphate Pathway | ||||
| Gluconeogenesis | ||||
| Reactome | Gluconeogenesis | |||
| WikiPathways | Glycolysis and Gluconeogenesis | |||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Allosteric FBPase inhibitors gain 10(5) times in potency when simultaneously binding two neighboring AMP sites. Bioorg Med Chem Lett. 2008 Aug 15;18(16):4708-12. | |||
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