Drug Information
Drug General Information | Top | |||
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Drug ID |
D0H6TP
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Former ID |
DAP000830
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Drug Name |
Monobenzone
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Synonyms |
Agerite; Alba; Benoquin; Benzoquin; Carmifal; Depigman; Dermochinona; Leucodinine; Monobenzon; Monobenzona; Monobenzonum; PBP; Pigmex; Superlite; Agerite alba; Benzyl hydroquinone; Hydrochinon monobenzylether; Hydrochinon monobenzylether [Czech]; Hydroquinone benzyl ether; Hydroquinone monobenzyl ether; ICN brand of monobenzone; Monobenzone [INN]; Monobenzyl Ether of Hydroquinone; Monobenzyl ether hydroquinone; Monobenzyl hydroquinone; Alba-Dome; Benoquin (TN); Benoquin, Monobenzone; Benzyl p-hydroxyphenyl ether; Carmifal(TN); Depigman (TN); Dermochinona (TN); HYDROQUINONE MONOBENZYL ETHER, N F; Leucodinine (TN); Monobenzon (TN); Monobenzona [INN-Spanish]; Monobenzonum [INN-Latin]; Novo-depigman; P-BENZYLOXYPHENOL; P-Hydroxyphenyl benzyl ether; Pigmex (TN); Superlite (TN); Superlite (antioxidant); Monobenzone (USP/INN); P-(BENZYLOXY)PHENOL; 4-(Benzyl-Oxy)Phenol; 4-(Benzyloxy)phenol; 4-(Benzyloxyl)phenol; 4-(Phenylmethoxy)phenol; 4-Benzyloxyphenol; 4-benzyloxy phenol; 4-phenylmethoxy-phenol; 4-phenylmethoxyphenol
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Drug Type |
Small molecular drug
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Indication | Vitiligo [ICD-11: ED63.0; ICD-10: L80-L99, L80; ICD-9: 709.01] | Approved | [1], [2] | |
Therapeutic Class |
Dermatologic Agents
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Structure |
Download2D MOL |
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Formula |
C13H12O2
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Canonical SMILES |
C1=CC=C(C=C1)COC2=CC=C(C=C2)O
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InChI |
1S/C13H12O2/c14-12-6-8-13(9-7-12)15-10-11-4-2-1-3-5-11/h1-9,14H,10H2
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InChIKey |
VYQNWZOUAUKGHI-UHFFFAOYSA-N
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CAS Number |
CAS 103-16-2
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PubChem Compound ID | ||||
PubChem Substance ID |
68818, 91829, 6305368, 7847054, 8155204, 10502657, 10561358, 11112252, 11466940, 11468060, 11486709, 12016119, 15114599, 24849729, 29226461, 46507466, 47206799, 47291387, 47440557, 47662549, 47960021, 48185249, 48413876, 48422013, 49699206, 49829901, 49857419, 50100397, 50415393, 51072586, 53787760, 56368754, 57324378, 85171308, 87564047, 92125750, 92166547, 92714762, 93165455, 93616918, 99216657, 99343594, 103469378, 103810887, 103914634, 104253287, 104315544, 104667978, 117535182, 117615110
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ChEBI ID |
CHEBI:34380
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ADReCS Drug ID | BADD_D01493 | |||
SuperDrug ATC ID |
D11AX13
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SuperDrug CAS ID |
cas=000103162
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Target and Pathway | Top | |||
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Target(s) | Tyrosinase (TYR) | Target Info | Inhibitor | [3] |
BioCyc | (S)-reticuline biosynthesis | |||
Eumelanin biosynthesis | ||||
L-dopachrome biosynthesis | ||||
KEGG Pathway | Tyrosine metabolism | |||
Riboflavin metabolism | ||||
Metabolic pathways | ||||
Melanogenesis | ||||
Pathwhiz Pathway | Riboflavin Metabolism | |||
Tyrosine Metabolism | ||||
WikiPathways | Dopamine metabolism |
References | Top | |||
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REF 1 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 6830). | |||
REF 2 | FDA Approved Drug Products from FDA Official Website. 2009. Application Number: (NDA) 008173. | |||
REF 3 | Identification of an Alkylhydroquinone from Rhus succedanea as an Inhibitor of Tyrosinase and Melanogenesis. J Agric Food Chem. 2009 Mar 25;57(6):2200-5. |
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