Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0H5CD
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| Former ID |
DIB007835
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| Drug Name |
GI-129471
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| Synonyms |
GI-129471; GI 129471; CHEMBL114427; 130370-59-1; AC1NX8L8; SCHEMBL6838720; DTXSID60156496; gi129471; BDBM50069608; GW9471; GW-9471; (2R-(1(S*),2R*,3S*))-N4-Hydroxy-N1-(2-(methylamino)-2-oxo-1-(phenylmethyl)ethyl)-2-(2-methylpropyl)-3-((phenylthio)methyl)butanediamide; Butanediamide, N4-hydroxy-N1-(2-(methylamino)-2-oxo-1-(phenylmethyl)ethyl)-2-(2-methylpropyl)-3-((phenylthio)methyl)-, (2R-(1(S*),2R*,3S*))-
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| Drug Type |
Small molecular drug
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| Indication | Inflammation [ICD-11: 1A00-CA43.1] | Terminated | [1] | |
| Company |
Glaxo Inc
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| Structure |
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Download2D MOL |
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| Formula |
C25H33N3O4S
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| Canonical SMILES |
CC(C)CC(C(CSC1=CC=CC=C1)C(=O)NO)C(=O)NC(CC2=CC=CC=C2)C(=O)NC
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| InChI |
1S/C25H33N3O4S/c1-17(2)14-20(21(24(30)28-32)16-33-19-12-8-5-9-13-19)23(29)27-22(25(31)26-3)15-18-10-6-4-7-11-18/h4-13,17,20-22,32H,14-16H2,1-3H3,(H,26,31)(H,27,29)(H,28,30)/t20-,21+,22+/m1/s1
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| InChIKey |
UBFGIEDUTRCMEQ-FSSWDIPSSA-N
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| CAS Number |
CAS 130370-59-1
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Matrix metalloproteinase (MMP) | Target Info | Modulator | [2] |
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800006709) | |||
| REF 2 | Stimulation of matrix metalloproteinase-9 expression in human fibrosarcoma cells by synthetic matrix metalloproteinase inhibitors. Exp Cell Res. 2002 Apr 15;275(1):110-21. | |||
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