Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D0H2SY
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| Former ID |
DAP001231
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| Drug Name |
Oxybuprocaine
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| Synonyms |
Benoxil; Benoxinate; Butoxyaminobenzoyldiethylaminoethanol; Butoxyprocaine; Conjucain; Dorsacain; Novescine; Novesinol; Oxibuprocaina; Oxibuprocainum; Oxibuprokain; Oxybucaine; Oxybuprocainum; Oxyriprocaine; Prescaina; Benoxinate hydrochloride; Monofree oxybuprocaine; Oxybuprocaine HCL; Oxybuprocaine hydrochloride; S 749;Monofree oxybuprocaine (TN); Novesin (TN); Novesine (TN); Oxibuprocaina [INN-Spanish]; Oxybuprocaine (INN); Oxybuprocaine [INN:BAN]; Oxybuprocainum [INN-Latin]; Diethylaminoethyl-4-amino-3-butoxybenzoate; BENZOIC ACID, 4-AMINO-3-BUTOXY-, 2-(DIETHYLAMINO)ETHYL ESTER; Benzoic acid, 4-amino-3-butoxy-, 2-(diethylamino)ethyl ester (7CI,8CI,9CI); 2-(Diethylamino)ethyl 4-amino-3-butoxybenzoate; 2-(diethylamino)ethyl 4-amino-3-n-butoxybenzoate; 2-Diethylaminoethyl 4-amino-3-butoxybenzoate; 3-Butoxy-4-aminobenzoic acid 2-(diethylamino)ethyl ester; 3-Butoxy-4-aminobenzoic acid 2-diethylaminoethyl ester; 4-Amino-3-butoxy-2-(diethylamino)ethyl ester benzoic acid; 4-Amino-3-butoxy-benzoic acid 2-diethylamino-ethyl ester; 4-Amino-3-butoxybenzoic acid 2-(diethylamino)ethyl ester; 4-Amino-3-butoxybenzoicacid 2-diethylaminoethyl ester; 4-Amino-3-n-butoxy-benzoesaeure-diaethylaminoaethylester; 4-Amino-3-n-butoxy-benzoesaeure-diaethylaminoaethylester [German]
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| Drug Type |
Small molecular drug
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| Indication | Anaesthesia [ICD-11: 9A78.6; ICD-9: 338] | Approved | [1], [2] | |
| Therapeutic Class |
Anesthetics
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| Company |
Norvatis Phamaceuticals Corporation
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| Structure |
 |
Download2D MOL |
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| Formula |
C17H28N2O3
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| Canonical SMILES |
CCCCOC1=C(C=CC(=C1)C(=O)OCCN(CC)CC)N
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| InChI |
1S/C17H28N2O3/c1-4-7-11-21-16-13-14(8-9-15(16)18)17(20)22-12-10-19(5-2)6-3/h8-9,13H,4-7,10-12,18H2,1-3H3
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| InChIKey |
CMHHMUWAYWTMGS-UHFFFAOYSA-N
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| CAS Number |
CAS 99-43-4
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| PubChem Compound ID | ||||
| PubChem Substance ID |
841051, 5214240, 7980227, 8152845, 10539122, 11112575, 11466085, 11467205, 11485870, 14874159, 29223722, 46505399, 47365374, 47662470, 48259426, 48334674, 49698325, 49885584, 50100491, 50224342, 56320722, 56323957, 57322365, 85501766, 85787520, 96025006, 99245743, 103358745, 104306973, 117714298, 118312930, 123081044, 124801263, 125354048, 127645893, 131740430, 134224387, 134338470, 134971742, 137006537, 141665384, 143438151, 144040677, 160964232, 171578509, 175268839, 175442353, 178103700, 178125676, 179225186
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| ChEBI ID |
CHEBI:309594
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| SuperDrug ATC ID |
D04AB03; S01HA02
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| SuperDrug CAS ID |
cas=000099434
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Sodium channel unspecific (NaC) | Target Info | Blocker | [3] |
| KEGG Pathway | Dopaminergic synapse | |||
| Reactome | Interaction between L1 and Ankyrins | |||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 7123). | |||
| REF 2 | Drug information of Oxybuprocaine, 2008. eduDrugs. | |||
| REF 3 | Intrathecal oxybuprocaine and proxymetacaine produced potent and long-lasting spinal anesthesia in rats. Neurosci Lett. 2009 May 1;454(3):249-53. | |||
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