Drug Information
Drug General Information | Top | |||
---|---|---|---|---|
Drug ID |
D0H2IA
|
|||
Former ID |
DIB019112
|
|||
Drug Name |
CGP 56999A
|
|||
Synonyms |
CGP56999A; CGP-56999A
Click to Show/Hide
|
|||
Drug Type |
Small molecular drug
|
|||
Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
Structure |
Download2D MOL
|
|||
Formula |
C19H30NO5P
|
|||
Canonical SMILES |
CC(C1=CC(=CC=C1)C(=O)O)NCC(CP(=O)(CC2CCCCC2)O)O
|
|||
InChI |
1S/C19H30NO5P/c1-14(16-8-5-9-17(10-16)19(22)23)20-11-18(21)13-26(24,25)12-15-6-3-2-4-7-15/h5,8-10,14-15,18,20-21H,2-4,6-7,11-13H2,1H3,(H,22,23)(H,24,25)/t14-,18+/m1/s1
|
|||
InChIKey |
JCFULPDIJOVUHP-KDOFPFPSSA-N
|
|||
PubChem Compound ID | ||||
PubChem Substance ID |
Target and Pathway | Top | |||
---|---|---|---|---|
Target(s) | Gamma-aminobutyric acid B receptor (GABBR) | Target Info | Antagonist | [2] |
KEGG Pathway | cAMP signaling pathway | |||
Neuroactive ligand-receptor interaction | ||||
GABAergic synapse | ||||
Estrogen signaling pathway | ||||
Morphine addiction | ||||
Reactome | Activation of G protein gated Potassium channels | |||
G alpha (i) signalling events | ||||
Class C/3 (Metabotropic glutamate/pheromone receptors) | ||||
Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits | ||||
WikiPathways | GPCRs, Class C Metabotropic glutamate, pheromone | |||
Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell | ||||
Potassium Channels | ||||
GPCR ligand binding | ||||
GPCR downstream signaling |
References | Top | |||
---|---|---|---|---|
REF 1 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 1071). | |||
REF 2 | Expression cloning of GABA(B) receptors uncovers similarity to metabotropic glutamate receptors. Nature. 1997 Mar 20;386(6622):239-46. |
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.