Drug Information
Drug General Information | Top | |||
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Drug ID |
D0H0IA
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Former ID |
DIB005487
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Drug Name |
WY-28342
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Indication | Rheumatoid arthritis [ICD-11: FA20] | Terminated | [1] | |
Company |
Wyeth-Ayerst International Inc
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Structure |
![]() |
Download2D MOL |
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Formula |
C19H23NO
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Canonical SMILES |
CC1=CC=C(C=C1)C(C2=NC3=C(CCCCC3)C=C2C)O
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InChI |
1S/C19H23NO/c1-13-8-10-15(11-9-13)19(21)18-14(2)12-16-6-4-3-5-7-17(16)20-18/h8-12,19,21H,3-7H2,1-2H3
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InChIKey |
KLGYQZZTJRHYIN-UHFFFAOYSA-N
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PubChem Compound ID |
Target and Pathway | Top | |||
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Target(s) | Arachidonate 5-lipoxygenase (5-LOX) | Target Info | Modulator | [2] |
Prostaglandin G/H synthase (COX) | Target Info | Modulator | [2] | |
BioCyc | Aspirin-triggered lipoxin biosynthesis | |||
Resolvin D biosynthesis | ||||
Leukotriene biosynthesis | ||||
Lipoxin biosynthesis | ||||
Aspirin triggered resolvin D biosynthesis | ||||
Aspirin triggered resolvin E biosynthesis | ||||
KEGG Pathway | Arachidonic acid metabolism | |||
Metabolic pathways | ||||
Serotonergic synapse | ||||
Ovarian steroidogenesis | ||||
Toxoplasmosis | ||||
NetPath Pathway | IL4 Signaling Pathway | |||
Pathwhiz Pathway | Arachidonic Acid Metabolism | |||
WikiPathways | Vitamin D Receptor Pathway | |||
Arachidonic acid metabolism | ||||
Eicosanoid Synthesis | ||||
Selenium Micronutrient Network |
References | Top | |||
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REF 1 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800005582) | |||
REF 2 | Synthesis and antiinflammatory activity of certain 5,6,7,8-tetrahydroquinolines and related compounds. J Med Chem. 1995 Apr 28;38(9):1473-81. |
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