Drug Information
Drug General Information | Top | |||
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Drug ID |
D0GZ8Q
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Drug Name |
Toremifene
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Synonyms |
Farestone; Z-Toremifene; Toremifeno; Toremifenum; Toremifenum [Latin]; Toremifeno [Spanish]; FC-1157a; GTx 006; Toremifene [INN:BAN]; UNII-7NFE54O27T; GTx-006
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Drug Type |
Small molecular drug
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Indication | Coronavirus Disease 2019 (COVID-19) [ICD-11: 1D6Y] | Investigative | [1] | |
Therapeutic Class |
Antiviral Agents
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Structure |
Download2D MOL |
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Formula |
C26H28ClNO
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Canonical SMILES |
CN(C)CCOC1=CC=C(C=C1)C(=C(CCCl)C2=CC=CC=C2)C3=CC=CC=C3
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InChI |
1S/C26H28ClNO/c1-28(2)19-20-29-24-15-13-23(14-16-24)26(22-11-7-4-8-12-22)25(17-18-27)21-9-5-3-6-10-21/h3-16H,17-20H2,1-2H3/b26-25-
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InChIKey |
XFCLJVABOIYOMF-QPLCGJKRSA-N
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CAS Number |
CAS 89778-26-7
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PubChem Compound ID | ||||
ChEBI ID |
CHEBI:9635
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Target and Pathway | Top | |||
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Target(s) | COVID-19 non-structural protein 14 (nsp14) | Target Info | Inhibitor | [1] |
COVID-19 spike glycoprotein (S) | Target Info | Inhibitor | [1] |
References | Top | |||
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REF 1 | Repurposing of FDA-Approved Toremifene to Treat COVID-19 by Blocking the Spike Glycoprotein and NSP14 of SARS-CoV-2. June 5, 2020. |
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