Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D0GT8N
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| Former ID |
DNC009917
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| Drug Name |
NM-PP1
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| Synonyms |
1-NM-PP1; 221244-14-0; PP1 Analog II, 1NM-PP1; 1-tert-butyl-3-(naphthalen-1-ylmethyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine; NM-PP1; Mutant Kinases Inhibitor II; 1NM-PP1(PP1 Analog II); AC1NP9I6; CHEMBL573578; 1 NM-PP1; CHEBI:52309; 4-Amino-1-tert-butyl-3-(1'-naphthylmethyl)pyrazolo[3,4-d]pyrimidine; 1-(tert-butyl)-3-(naphthalen-1-ylmethyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine; MMV676599; 1-(1,1-dimethylethyl)-3-(1-naphthalenylmethyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine; W-201917; C20H21N5
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C20H21N5
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| Canonical SMILES |
CC(C)(C)N1C2=NC=NC(=C2C(=N1)CC3=CC=CC4=CC=CC=C43)N
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| InChI |
1S/C20H21N5/c1-20(2,3)25-19-17(18(21)22-12-23-19)16(24-25)11-14-9-6-8-13-7-4-5-10-15(13)14/h4-10,12H,11H2,1-3H3,(H2,21,22,23)
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| InChIKey |
GDQXJQSQYMMKRA-UHFFFAOYSA-N
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| CAS Number |
CAS 221244-14-0
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| PubChem Compound ID | ||||
| PubChem Substance ID |
7652214, 8577944, 14777531, 26759391, 39002667, 49645644, 49815672, 53800582, 57581434, 58608236, 76556496, 99302765, 103694299, 104139756, 113776121, 124792262, 125333804, 127938937, 134347122, 140290968, 144080829, 152343755, 162254028, 163124445, 163663961, 163687462, 163726964, 170558538, 174006637, 175607432, 178102650, 178111817, 179042910, 204361342, 208012745, 208013107, 208264803, 208265645, 210275013, 210280651, 223394633, 228125047, 250134311, 251910631, 252160545, 252214173, 252229221, 252457406, 252465372, 252672132
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| ChEBI ID |
CHEBI:52309
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| References | Top | |||
|---|---|---|---|---|
| REF 1 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 6028). | |||
| REF 2 | The selectivity of protein kinase inhibitors: a further update. Biochem J. 2007 Dec 15;408(3):297-315. | |||
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