Drug Information
Drug General Information | Top | |||
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Drug ID |
D0GH7L
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Drug Name |
PRN1008
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Synonyms |
LCFFREMLXLZNHE-GBOLQPHISA-N; SCHEMBL15506003; BDBM143212; US8940744, 31; (R,E)-2-(3-(4-amino-3-(2-fluoro-4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidine-1-carbonyl)-4-methyl-4-(4-(oxetan-3-yl)piperazin-1-yl)pent-2-enenitrile
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Indication | Pemphigus vulgaris [ICD-11: EB40; ICD-10: L10.0, L10.1; ICD-9: 694.4] | Phase 2 | [1], [2] | |
Company |
Principia Biopharma South San Francisco, CA
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Structure |
Download2D MOL |
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Formula |
C36H40FN9O3
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Canonical SMILES |
CC(C)(C=C(C#N)C(=O)N1CCCC(C1)N2C3=NC=NC(=C3C(=N2)C4=C(C=C(C=C4)OC5=CC=CC=C5)F)N)N6CCN(CC6)C7COC7
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InChI |
1S/C36H40FN9O3/c1-36(2,45-15-13-43(14-16-45)26-21-48-22-26)18-24(19-38)35(47)44-12-6-7-25(20-44)46-34-31(33(39)40-23-41-34)32(42-46)29-11-10-28(17-30(29)37)49-27-8-4-3-5-9-27/h3-5,8-11,17-18,23,25-26H,6-7,12-16,20-22H2,1-2H3,(H2,39,40,41)/b24-18+/t25-/m1/s1
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InChIKey |
LCFFREMLXLZNHE-GBOLQPHISA-N
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CAS Number |
CAS 1575596-29-0
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PubChem Compound ID |
References | Top | |||
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REF 1 | Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA) | |||
REF 2 | Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA) |
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