Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0GH0Z
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| Drug Name |
PMID25522065-Compound-41
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| Drug Type |
Small molecular drug
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| Company |
RICHTER GEDEON NYRT [HU]
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| Structure |
 |
Download2D MOL |
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| Formula |
C26H24ClN3O4S
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| Canonical SMILES |
COC1=C(C=CC(=C1)N2C=NC3=C(C2=O)SC(=C3)C4=CC=C(C=C4)Cl)OCCN5CC6(C5)COC6
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| InChI |
1S/C26H24ClN3O4S/c1-32-22-10-19(6-7-21(22)34-9-8-29-12-26(13-29)14-33-15-26)30-16-28-20-11-23(35-24(20)25(30)31)17-2-4-18(27)5-3-17/h2-7,10-11,16H,8-9,12-15H2,1H3
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| InChIKey |
RYWKRAVYOFTFPJ-UHFFFAOYSA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Melanin-concentrating hormone receptor 1 (MCHR1) | Target Info | Antagonist | [1] |
| Target's Patent Info | Melanin-concentrating hormone receptor 1 (MCHR1) | Target's Patent Info | [1] | |
| KEGG Pathway | Neuroactive ligand-receptor interaction | |||
| Reactome | Peptide ligand-binding receptors | |||
| G alpha (q) signalling events | ||||
| G alpha (i) signalling events | ||||
| WikiPathways | GPCRs, Class A Rhodopsin-like | |||
| Gastrin-CREB signalling pathway via PKC and MAPK | ||||
| GPCR ligand binding | ||||
| GPCR downstream signaling | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Novel MCH1 receptor antagonists: a patent review.Expert Opin Ther Pat. 2015 Feb;25(2):193-207. | |||
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