Drug Information
Drug General Information | Top | |||
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Drug ID |
D0G8NJ
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Former ID |
DAP000910
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Drug Name |
Rescinnamine
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Synonyms |
Anapral; Anaprel; Apolon; Apoterin; Cartric; Cinamine; Cinatabs; Cinnaloid; Cinnasil; Moderil; Normorescina; Paresinan; Raupyrol; Raurescin; Raurescine; Recinnamine; Recitensina; Rescaloid; Rescamin; Rescidan; Rescin; Rescinamina; Rescinnamin; Rescinnamina; Rescinnaminum; Rescinpal; Rescisan; Rescitens; Resealoid; Reserpinene; Reserpinin; Reserpinine; Resipal; Reskinnamin; Rozex; Scinnamina; Tenamine; Tuareg; Apoterin S; Methyl trimethoxycinnamoylreserpate; Rescinnamina [DCIT]; Trimethoxy cinnamoyl reserpate de methyl; Trimethoxy cinnamoyl reserpate de methyl [French]; Trimethoxycinnamoyl methyl reserpate; Tsuruselpi S; Anaprel (TN); Cinnasil (TN); Moderil (TN); NP-011016; Rescinamina [INN-Spanish]; Rescinnamine (VAN); Rescinnaminum [INN-Latin]; Resepinine (C35 alkaloid); Reserpinine (C35 alkaloid); Reserpinine (VAN); Tsuruselpi S (TN); Rescinnamine (JAN/INN); Rescinnamine [BAN:INN:JAN]; Methyl reserpate 3,4,5-trimethoxycinnamic acid ester; Reserpic acid methyl ester 3,4,5-trimethoxycinnamate; Methyl 18-O-(3,4,5-trimethoxycinnamoyl)reserpate; O-(3,4,5-Trimethoxy-trans-cinnamoyl) methyl reserpate; 3,4,5-Trimethoxycinnamic acid, methyl reserpate; 3,4,5-Trimethoxycinnamoyl methyl reserpate; 3,4,5-Trimethylcinnamic acid, ester with methyl reserpate; 3,4,5-Trimethylcinnamoyl methyl reserpate
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Drug Type |
Small molecular drug
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Indication | Hypertension [ICD-11: BA00-BA04; ICD-9: 401] | Approved | [1], [2] | |
Therapeutic Class |
Antihypertensive Agents
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Structure |
Download2D MOL |
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Formula |
C35H42N2O9
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Canonical SMILES |
COC1C(CC2CN3CCC4=C(C3CC2C1C(=O)OC)NC5=C4C=CC(=C5)OC)OC(=O)C=CC6=CC(=C(C(=C6)OC)OC)OC
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InChI |
1S/C35H42N2O9/c1-40-21-8-9-22-23-11-12-37-18-20-15-29(46-30(38)10-7-19-13-27(41-2)33(43-4)28(14-19)42-3)34(44-5)31(35(39)45-6)24(20)17-26(37)32(23)36-25(22)16-21/h7-10,13-14,16,20,24,26,29,31,34,36H,11-12,15,17-18H2,1-6H3/b10-7+/t20-,24+,26-,29-,31+,34+/m1/s1
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InChIKey |
SZLZWPPUNLXJEA-QEGASFHISA-N
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CAS Number |
CAS 24815-24-5
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PubChem Compound ID | ||||
PubChem Substance ID |
8770, 79429, 597356, 7847266, 8138008, 8616456, 10321534, 14789939, 39289912, 46530467, 47515483, 47515484, 47662471, 47885571, 48035309, 48334675, 48416513, 48424034, 49698557, 49855219, 56463114, 57357943, 75304571, 85789351, 85789400, 92125322, 95156792, 103636520, 103914025, 121362993, 124800786, 134338187, 134995503, 135727524, 137003688, 137241862, 141909708, 164814309, 178103676, 179116876, 184547043, 198962755, 226542531, 241044490, 251895606, 252356449
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ChEBI ID |
CHEBI:28572
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ADReCS Drug ID | BADD_D01925 | |||
SuperDrug ATC ID |
C02AA01
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SuperDrug CAS ID |
cas=024815245
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Target and Pathway | Top | |||
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Target(s) | Angiotensin-converting enzyme (ACE) | Target Info | Inhibitor | [3] |
KEGG Pathway | Renin-angiotensin system | |||
Chagas disease (American trypanosomiasis) | ||||
Hypertrophic cardiomyopathy (HCM) | ||||
Pathwhiz Pathway | Angiotensin Metabolism | |||
Reactome | Metabolism of Angiotensinogen to Angiotensins | |||
WikiPathways | ACE Inhibitor Pathway | |||
Metabolism of Angiotensinogen to Angiotensins |
References | Top | |||
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REF 1 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 7098). | |||
REF 2 | FDA Approved Drug Products from FDA Official Website. 2009. Application Number: (NDA) 010686. | |||
REF 3 | Colorimetric determination of indolic drugs. Pak J Pharm Sci. 2005 Apr;18(2):48-51. |
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