Drug Information
Drug General Information | Top | |||
---|---|---|---|---|
Drug ID |
D0G6IO
|
|||
Former ID |
DNC013589
|
|||
Drug Name |
1-(4-bromophenyl)-3-hydroxyurea
|
|||
Synonyms |
1-(4-bromophenyl)-3-hydroxyurea; CHEMBL259767; 89677-50-9; AC1N5XPQ; AC1Q7DJ1; SCHEMBL5443582; QFELVVGTIKGYJL-UHFFFAOYSA-N; ZINC396739; N-(4-bromophenyl)-N'-hydroxyurea; BDBM50377111; AKOS024335516
Click to Show/Hide
|
|||
Drug Type |
Small molecular drug
|
|||
Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
Structure |
Download2D MOL |
|||
Formula |
C7H7BrN2O2
|
|||
Canonical SMILES |
C1=CC(=CC=C1NC(=O)NO)Br
|
|||
InChI |
1S/C7H7BrN2O2/c8-5-1-3-6(4-2-5)9-7(11)10-12/h1-4,12H,(H2,9,10,11)
|
|||
InChIKey |
QFELVVGTIKGYJL-UHFFFAOYSA-N
|
|||
PubChem Compound ID |
Target and Pathway | Top | |||
---|---|---|---|---|
Target(s) | Tyrosinase (TYR) | Target Info | Inhibitor | [1] |
BioCyc | (S)-reticuline biosynthesis | |||
Eumelanin biosynthesis | ||||
L-dopachrome biosynthesis | ||||
KEGG Pathway | Tyrosine metabolism | |||
Riboflavin metabolism | ||||
Metabolic pathways | ||||
Melanogenesis | ||||
Pathwhiz Pathway | Riboflavin Metabolism | |||
Tyrosine Metabolism | ||||
WikiPathways | Dopamine metabolism |
References | Top | |||
---|---|---|---|---|
REF 1 | Analogues of N-hydroxy-N'-phenylthiourea and N-hydroxy-N'-phenylurea as inhibitors of tyrosinase and melanin formation. Bioorg Med Chem Lett. 2008 Jun 15;18(12):3607-10. |
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.