Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0G3RZ
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| Former ID |
DNC010223
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| Drug Name |
6-(4-Methylpiperazin-1-yl)-9H-purin-2-amine
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| Synonyms |
6-(4-Methylpiperazin-1-yl)-9H-purin-2-amine; CHEMBL594694; 1196993-60-8; SCHEMBL20093538; MolPort-039-193-873; BBL036459; STL490826; ZINC45352375; BDBM50304514
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C10H15N7
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| Canonical SMILES |
CN1CCN(CC1)C2=NC(=NC3=C2NC=N3)N
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| InChI |
1S/C10H15N7/c1-16-2-4-17(5-3-16)9-7-8(13-6-12-7)14-10(11)15-9/h6H,2-5H2,1H3,(H3,11,12,13,14,15)
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| InChIKey |
HZZXEPZFOVOWIN-UHFFFAOYSA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Histamine H4 receptor (H4R) | Target Info | Inhibitor | [1] |
| KEGG Pathway | Neuroactive ligand-receptor interaction | |||
| Reactome | Histamine receptors | |||
| G alpha (i) signalling events | ||||
| WikiPathways | GPCR ligand binding | |||
| GPCR downstream signaling | ||||
| GPCRs, Other | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | 2,4-Diaminopyrimidines as histamine H4 receptor ligands--Scaffold optimization and pharmacological characterization. Bioorg Med Chem. 2009 Oct 15;17(20):7186-96. | |||
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