Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0G2VT
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| Former ID |
DCL001007
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| Drug Name |
SUN-11031
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| Synonyms |
6,6,6-trifluoromethionine; AC1L5KZ2; SCHEMBL245985; CTK1D7491; NSC73030; NSC-73030; 2-Amino-4-(trifluoromethylthio)butyric acid; 2-amino-4-(trifluoromethylsulfanyl)butanoic acid
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| Drug Type |
Small molecular drug
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| Indication | Anorexia nervosa cachexia [ICD-11: 6B80; ICD-10: F50.0-F50.1; ICD-9: 307.1, 799.4] | Terminated | [1] | |
| Company |
Daiichi Suntory Pharma
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| Structure |
 |
Download2D MOL |
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| Formula |
C5H8F3NO2S
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| Canonical SMILES |
C(CSC(F)(F)F)C(C(=O)O)N
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| InChI |
1S/C5H8F3NO2S/c6-5(7,8)12-2-1-3(9)4(10)11/h3H,1-2,9H2,(H,10,11)
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| InChIKey |
YLJLTSVBCXYTQK-UHFFFAOYSA-N
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| PubChem Compound ID | ||||
| PubChem Substance ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Growth hormone secretagogue receptor 1 (GHSR) | Target Info | Agonist | [1] |
| KEGG Pathway | cAMP signaling pathway | |||
| Neuroactive ligand-receptor interaction | ||||
| NetPath Pathway | Leptin Signaling Pathway | |||
| Reactome | Peptide ligand-binding receptors | |||
| G alpha (q) signalling events | ||||
| WikiPathways | GPCRs, Class A Rhodopsin-like | |||
| Gastrin-CREB signalling pathway via PKC and MAPK | ||||
| Peptide GPCRs | ||||
| GPCR ligand binding | ||||
| GPCR downstream signaling | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Emerging drugs for eating disorder treatment. Expert Opin Emerg Drugs. 2006 May;11(2):315-36. | |||
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