Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0G2AK
|
|||
| Former ID |
DNC007097
|
|||
| Drug Name |
3-methoxy-N',2-diphenylquinoline-4-carbohydrazide
|
|||
| Synonyms |
CHEMBL218717; SCHEMBL3963611; WQHSKTAHWLQAGK-UHFFFAOYSA-N; BDBM50194593; 3-methyloxy-N',2-diphenyl-4-quinolinecarbohydrazide
Click to Show/Hide
|
|||
| Drug Type |
Small molecular drug
|
|||
| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
 |
Download2D MOL |
||
| Formula |
C23H19N3O2
|
|||
| Canonical SMILES |
COC1=C(C2=CC=CC=C2N=C1C3=CC=CC=C3)C(=O)NNC4=CC=CC=C4
|
|||
| InChI |
1S/C23H19N3O2/c1-28-22-20(23(27)26-25-17-12-6-3-7-13-17)18-14-8-9-15-19(18)24-21(22)16-10-4-2-5-11-16/h2-15,25H,1H3,(H,26,27)
|
|||
| InChIKey |
WQHSKTAHWLQAGK-UHFFFAOYSA-N
|
|||
| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Neuromedin-K receptor (TACR3) | Target Info | Inhibitor | [1] |
| KEGG Pathway | Calcium signaling pathway | |||
| Neuroactive ligand-receptor interaction | ||||
| Reactome | G alpha (q) signalling events | |||
| WikiPathways | Gastrin-CREB signalling pathway via PKC and MAPK | |||
| Peptide GPCRs | ||||
| GPCR ligand binding | ||||
| GPCR downstream signaling | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | N',2-diphenylquinoline-4-carbohydrazide based NK3 receptor antagonists. Bioorg Med Chem Lett. 2006 Nov 15;16(22):5748-51. | |||
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.