Drug Information
Drug General Information | Top | |||
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Drug ID |
D0G1VS
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Former ID |
DNC004154
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Drug Name |
UK-78282
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Synonyms |
UK-78282; CHEMBL9653; AC1LCVJE; UK 78282; UK-78282 monohydrochloride; CHEBI:35042; C13848; 4-(benzhydryloxymethyl)-1-[3-(4-methoxyphenyl)propyl]piperidine; ZINC3798289; DNC004154; BDBM50098785; NCGC00370962-01; AJ-45641; RT-016190; J-006878
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Drug Type |
Small molecular drug
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Indication | Inflammation [ICD-11: 1A00-CA43.1] | Terminated | [1] | |
Structure |
Download2D MOL |
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Formula |
C29H35NO2
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Canonical SMILES |
COC1=CC=C(C=C1)CCCN2CCC(CC2)COC(C3=CC=CC=C3)C4=CC=CC=C4
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InChI |
1S/C29H35NO2/c1-31-28-16-14-24(15-17-28)9-8-20-30-21-18-25(19-22-30)23-32-29(26-10-4-2-5-11-26)27-12-6-3-7-13-27/h2-7,10-17,25,29H,8-9,18-23H2,1H3
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InChIKey |
WRTXEGOLODUQIE-UHFFFAOYSA-N
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PubChem Compound ID | ||||
ChEBI ID |
CHEBI:35042
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Target and Pathway | Top | |||
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Target(s) | Voltage-gated potassium channel Kv1.3 (KCNA3) | Target Info | Inhibitor | [2] |
Reactome | Voltage gated Potassium channels | |||
WikiPathways | Potassium Channels | |||
BDNF signaling pathway |
References | Top | |||
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REF 1 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800009179) | |||
REF 2 | Angular methoxy-substituted furo- and pyranoquinolinones as blockers of the voltage-gated potassium channel Kv1.3. J Med Chem. 2001 Apr 12;44(8):1249-56. |
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