Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0FW2W
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| Former ID |
DNC008351
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| Drug Name |
4-(2,4-dichloro-phenoxy)-4'-fluoro-biphenyl-3-ol
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| Synonyms |
2-(2,4-dichlorophenoxy)-5-(4-fluorophenyl)phenol; Triclosan derivative, 19; CHEMBL260979
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C18H11Cl2FO2
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| Canonical SMILES |
C1=CC(=CC=C1C2=CC(=C(C=C2)OC3=C(C=C(C=C3)Cl)Cl)O)F
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| InChI |
1S/C18H11Cl2FO2/c19-13-4-8-17(15(20)10-13)23-18-7-3-12(9-16(18)22)11-1-5-14(21)6-2-11/h1-10,22H
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| InChIKey |
LFNMTUYVBXAAKI-UHFFFAOYSA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Plasmodium Enoyl-ACP reductase (Malaria fabI) | Target Info | Inhibitor | [1] |
| References | Top | |||
|---|---|---|---|---|
| REF 1 | X-ray structural analysis of Plasmodium falciparum enoyl acyl carrier protein reductase as a pathway toward the optimization of triclosan antimalar... J Biol Chem. 2007 Aug 31;282(35):25436-44. | |||
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