Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0FQ6O
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| Former ID |
DIB013687
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| Drug Name |
Etarotene
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| Synonyms |
Ro-15-1570; Ro-15-1570/000
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| Drug Type |
Small molecular drug
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| Indication | Psoriasis vulgaris [ICD-11: EA90; ICD-9: 696] | Discontinued in Phase 3 | [1] | |
| Company |
Roche Holding AG
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| Structure |
 |
Download2D MOL |
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| Formula |
C25H32O2S
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| Canonical SMILES |
CCS(=O)(=O)C1=CC=C(C=C1)C=C(C)C2=CC3=C(C=C2)C(CCC3(C)C)(C)C
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| InChI |
1S/C25H32O2S/c1-7-28(26,27)21-11-8-19(9-12-21)16-18(2)20-10-13-22-23(17-20)25(5,6)15-14-24(22,3)4/h8-13,16-17H,7,14-15H2,1-6H3/b18-16+
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| InChIKey |
UDAZCXVIYSIEFX-FBMGVBCBSA-N
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| CAS Number |
CAS 87719-32-2
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Ribonuclease P protein (RPP) | Target Info | Modulator | [2] |
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800003576) | |||
| REF 2 | Retinoids inhibit human epidermal keratinocyte RNase P activity. Biol Chem. 2003 Mar;384(3):457-62. | |||
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