Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0FQ4W
|
|||
| Drug Name |
PMID25522065-Compound-13
|
|||
| Drug Type |
Small molecular drug
|
|||
| Company |
ASTRAZENECA AB ASTRAZENECA UK LIMITED JOHANSSON, Lars, Anders, Mikael
|
|||
| Structure |
 |
Download2D MOL |
||
| Formula |
C26H28N4O4
|
|||
| Canonical SMILES |
CC1=C(C=CC(=C1)OC2CN(C2)C(=O)C3=NN=C(O3)C4=CC=CC=C4)CN5CC6(C5)CCOC6
|
|||
| InChI |
1S/C26H28N4O4/c1-18-11-21(8-7-20(18)12-29-15-26(16-29)9-10-32-17-26)33-22-13-30(14-22)25(31)24-28-27-23(34-24)19-5-3-2-4-6-19/h2-8,11,22H,9-10,12-17H2,1H3
|
|||
| InChIKey |
FMNDCDNBXCVEBC-UHFFFAOYSA-N
|
|||
| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Melanin-concentrating hormone receptor 1 (MCHR1) | Target Info | Antagonist | [1] |
| Target's Patent Info | Melanin-concentrating hormone receptor 1 (MCHR1) | Target's Patent Info | [1] | |
| KEGG Pathway | Neuroactive ligand-receptor interaction | |||
| Reactome | Peptide ligand-binding receptors | |||
| G alpha (q) signalling events | ||||
| G alpha (i) signalling events | ||||
| WikiPathways | GPCRs, Class A Rhodopsin-like | |||
| Gastrin-CREB signalling pathway via PKC and MAPK | ||||
| GPCR ligand binding | ||||
| GPCR downstream signaling | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Novel MCH1 receptor antagonists: a patent review.Expert Opin Ther Pat. 2015 Feb;25(2):193-207. | |||
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.