Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0FN1P
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| Former ID |
DIB013758
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| Drug Name |
Saviprazole
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| Synonyms |
Hoe-731
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| Drug Type |
Small molecular drug
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| Indication | Peptic ulcer [ICD-11: DA61] | Terminated | [1] | |
| Company |
Hoechst AG
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| Structure |
 |
Download2D MOL |
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| Formula |
C15H10F7N3O2S2
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| Canonical SMILES |
C1=CN=C(C=C1OCC(C(C(F)(F)F)(F)F)(F)F)CS(=O)C2=NC3=CSC=C3N2
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| InChI |
1S/C15H10F7N3O2S2/c16-13(17,14(18,19)15(20,21)22)7-27-9-1-2-23-8(3-9)6-29(26)12-24-10-4-28-5-11(10)25-12/h1-5H,6-7H2,(H,24,25)
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| InChIKey |
ARFGGIRJBPTBPP-UHFFFAOYSA-N
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| CAS Number |
CAS 121617-11-6
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Gastric H(+)/K(+) ATPase (Proton pump) | Target Info | Modulator | [2] |
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800000579) | |||
| REF 2 | Gastric acid inhibitory profile of saviprazole (HOE 731) compared to omeprazole. Pharmacology. 1991;43(6):293-303. | |||
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