Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D0FF6S
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| Former ID |
DNC001572
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| Drug Name |
A-803467
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| Synonyms |
A-803467; 944261-79-4; A 803467; UNII-339LBH1395; A803467; 5-(4-chlorophenyl)-N-(3,5-dimethoxyphenyl)furan-2-carboxamide; 5-(4-CHLOROPHENYL)-N-(3,5-DIMETHOXYPHENYL)-2-FURANCARBOXAMIDE; CHEMBL250699; 339LBH1395; 5-4(-Chlorophenyl)-N-(3,5-dimethoxyphenyl)furan-2-carboxamide; MLS006011118; GTPL5734; SCHEMBL9275137; CTK5H6562; EX-A083; DTXSID90241480; AOB2888; MolPort-006-069-060; HMS3656L08; BCP04519; 2-Furancarboxamide, 5-(4-chlorophenyl)-N-(3,5-dimethoxyphenyl)-; BN0738; ABP001000; ZINC14982453; MFCD10574689; BDBM50212239; s2785
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| Drug Type |
Small molecular drug
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| Indication | Pain [ICD-11: MG30-MG3Z] | Investigative | [1] | |
| Therapeutic Class |
Analgesics
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| Structure |
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Download2D MOL |
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| Formula |
C19H16ClNO4
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| Canonical SMILES |
COC1=CC(=CC(=C1)NC(=O)C2=CC=C(O2)C3=CC=C(C=C3)Cl)OC
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| InChI |
1S/C19H16ClNO4/c1-23-15-9-14(10-16(11-15)24-2)21-19(22)18-8-7-17(25-18)12-3-5-13(20)6-4-12/h3-11H,1-2H3,(H,21,22)
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| InChIKey |
VHKBTPQDHDSBSP-UHFFFAOYSA-N
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| CAS Number |
CAS 944261-79-4
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| PubChem Compound ID | ||||
| PubChem Substance ID |
24421011, 26587033, 41797675, 57379643, 59315399, 103558202, 104088220, 123120895, 125334082, 126599116, 134340703, 134964450, 135698847, 136342196, 136946447, 144115519, 152159597, 152258313, 152343564, 152344391, 160647153, 162011775, 162205055, 162248715, 163210106, 163642963, 164838287, 174006291, 174531627, 178102360, 186014510, 196408549, 198975580, 203090181, 204380863, 223388656, 223705161, 234696506, 241173086, 241376196, 242059778, 249189738, 251971259, 252156920, 252160566, 252450469
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Voltage-gated sodium channel alpha Nav1.8 (SCN10A) | Target Info | Inhibitor | [2] |
| Reactome | Interaction between L1 and Ankyrins | |||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 5734). | |||
| REF 2 | Sensory neuron voltage-gated sodium channels as analgesic drug targets. Curr Opin Neurobiol. 2008 Aug;18(4):383-8. | |||
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